Cefuroxime axetil is a prodrug that is converted after oral administration into active cefuroxime. Cefuroxime inhibits bacterial cell-wall synthesis by binding to penicillin-binding proteins, resulting in damage and death of susceptible bacteria.
CEFAPRIME-500 contains cefuroxime axetil, a second-generation cephalosporin antibiotic. It is intended for the treatment of bacterial infections caused by microorganisms susceptible to cefuroxime.
How it works:
Who may be prescribed this medicine:
Cefuroxime has been extensively evaluated in clinical practice as a second-generation cephalosporin. Clinical studies have demonstrated its efficacy in a range of respiratory tract infections, otitis media, sinusitis, urinary tract infections, and skin infections caused by susceptible bacteria.
An important feature of cefuroxime is its activity against a range of gram-positive and gram-negative bacteria. However, effectiveness depends on the susceptibility of the specific pathogen. Like other antibiotics, cefuroxime does not treat viral infections and should not be used for self-treatment of colds or influenza.
Cefuroxime axetil is used to treat bacterial infections caused by susceptible microorganisms.
Depending on the clinical situation, it may be used for:
The medicine inhibits the growth and reproduction of susceptible bacteria by disrupting bacterial cell-wall formation.
The tablets should be taken orally after food, as administration after a meal improves absorption of cefuroxime axetil. The tablet should be swallowed whole with water and should not be chewed. The dosage and duration of treatment are determined by a healthcare professional according to the type and severity of infection, the patient's age, and kidney function. The dose should not be changed and treatment should not be discontinued without medical advice.
Difficulty breathing, swelling of the face or throat, severe skin reactions, or severe persistent diarrhea require prompt medical attention.
