How it works:
Alkylates DNA to inhibit cell replication
Targets rapidly dividing tumour cells
Exerts immunosuppressive effects in autoimmune conditions
Recommended for:
Patients with lymphomas, leukemias, multiple myeloma
Breast, ovarian, and lung cancer
Autoimmune disorders such as lupus and rheumatoid arthritis
To be used strictly under specialist supervision
Hodgkin's and non-Hodgkin's lymphoma
Acute and chronic leukemia
Breast, ovarian, and lung cancer
Multiple myeloma
Autoimmune conditions including systemic lupus erythematosus and nephritis
Take orally in a dosage precisely determined by the prescribing oncologist. Dosage depends on the diagnosis, body weight, and treatment regimen. Requires frequent monitoring of blood parameters and renal function.
Contraindications:
Hypersensitivity to cyclophosphamide
Active infections
Severe hepatic or renal impairment
Bone marrow suppression
Pregnancy and lactation
Side Effects:
Bone marrow suppression
Nausea, vomiting
Hair loss
Immunosuppression
Increased risk of infections
Hepatic and renal dysfunction
Cystitis, haematuria
