How it works:
Zoledronic acid is a third-generation bisphosphonate that inhibits osteoclast-mediated bone resorption. This action helps maintain bone density, lowers the risk of skeletal complications, and effectively treats hypercalcemia associated with cancer. It is widely used in patients with metastatic bone disease and those at high risk of fractures.
Recommended For:
Postmenopausal women with osteoporosis
Cancer patients with bone metastases
Patients with multiple myeloma
Individuals with malignancy-induced hypercalcemia
Adults at high risk of bone complications
Postmenopausal osteoporosis
Prevention and treatment of skeletal events in cancer patients
Malignancy-induced hypercalcemia
Paget’s disease in adults
ZOLDONAT 4mg is administered as an intravenous infusion over at least 15 minutes. The concentrate must be diluted before use. The dosing schedule depends on the specific condition and is determined by a healthcare provider.
Contraindications:
Hypocalcemia
Hypersensitivity to zoledronic acid or other bisphosphonates
Severe renal impairment
Pregnancy and lactation
Side Effects:
Fever and flu-like symptoms
Headache, bone and muscle pain
Hypocalcemia
Increased serum creatinine
Infusion site reactions
Rare cases of renal dysfunction
