Fibrin sealant replicates the final stage of the physiological coagulation cascade. When fibrinogen and thrombin are combined, fibrinogen is converted into fibrin, forming a stable fibrin clot. This clot provides:
The fibrin matrix is gradually degraded as natural tissue healing progresses.
Used by healthcare professionals in:
Fibrin sealants have been used globally for over three decades. Clinical studies demonstrate reduced intraoperative blood loss and faster time to hemostasis compared to conventional methods alone.
Meta-analyses indicate reduced transfusion requirements and lower rates of postoperative complications when fibrin sealants are used appropriately. Their safety and biocompatibility are well established in surgical practice.
The product works by forming a biological fibrin clot that provides both mechanical and biochemical hemostasis.
The product is intended for topical use only during surgical procedures. The components are mixed immediately before application according to the manufacturer’s instructions and applied in a thin layer to the bleeding surface. It must be administered by a trained medical professional under sterile conditions.
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