How it works:
Tenofovir Disoproxil Fumarate (TDF) is a prodrug of tenofovir, which inhibits the reverse transcriptase enzyme in HIV-1 and HBV. By blocking viral DNA replication, it reduces viral load and slows disease progression. It is commonly used in combination with other antiretroviral drugs.
Recommended for:
Adults and adolescents with HIV-1 infection as part of combination therapy
Patients with chronic hepatitis B
Individuals previously treated with nucleotide analogues
Only for patients over 12 years old (under medical supervision)
Treatment of HIV-1 in adults and adolescents
Treatment of chronic hepatitis B
The tablets are taken orally once daily, with or without food. Dosage and treatment duration are determined by the prescribing physician based on the patient’s condition and therapeutic goals.
Hypersensitivity to tenofovir or any of the excipients
Severe renal impairment
Children under 12 years
Use during pregnancy and lactation without medical supervision
Headache, fatigue
Nausea, diarrhoea
Impaired renal function
Decreased bone mineral density
Elevated serum creatinine
Rash or allergic skin reactions
