TUDOBEST (tenofovir disoproxil) is a prodrug converted in the body to active tenofovir, which inhibits reverse transcriptase and blocks viral replication of HIV and hepatitis B virus.
Recommended for:
Adults and adolescents with confirmed HIV-1 infection
Patients with chronic hepatitis B
As part of combination antiretroviral therapy
Those switching from other regimens or initiating first-line treatment
HIV-1 infection
Chronic hepatitis B
Take orally once daily with or without food. Always use under medical supervision as part of a combination therapy regimen.
Contraindications:
Hypersensitivity to tenofovir or excipients
Severe renal impairment
Under 12 years of age
Use with nephrotoxic agents
Side Effects:
Diarrhoea, nausea
Elevated creatinine
Decreased bone mineral density
Headache, fatigue
Rash, itching