How it works:
Pantoprazole is a proton pump inhibitor that blocks the final step in gastric acid production. It effectively reduces acid levels, protects the gastric lining, and aids in the healing of ulcers and erosions in the gastrointestinal tract.
Recommended for:
Patients with peptic ulcers or duodenal ulcers
Those with acute GERD symptoms
Zollinger-Ellison syndrome
When oral therapy is not possible
Hospitalised patients with risk of gastrointestinal bleeding
Erosive and ulcerative conditions of the stomach and duodenum
Gastroesophageal reflux disease (GERD)
Stress ulcer prophylaxis in hospitalised patients
Zollinger-Ellison syndrome and other hypersecretory disorders
Pantoprazole is administered intravenously, usually at a dose of 40 mg once daily. It is typically used as short-term therapy until the patient can transition to oral treatment. The powder must be reconstituted prior to injection as per physician's instructions.
Contraindications:
Hypersensitivity to pantoprazole or excipients
Paediatric use (under 18 years old)
Severe hepatic impairment
Concomitant use with atazanavir
Side effects:
Headache
Diarrhoea or constipation
Nausea, bloating
Injection site reactions
Elevated liver enzymes
Rare: allergic reactions, hypomagnesaemia