Mechanism of Action:
- Agonist of GPR54 receptors (KISS1R) in hypothalamus
- Stimulates secretion of gonadotropin-releasing hormone (GnRH)
- Increases production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
- Activates pulsatile secretion of sex hormones
Recommended for:
- Patients with hypogonadotropic hypogonadism
- Individuals with fertility disorders and ovulatory dysfunction
- Athletes with suppressed sexual function after anabolic steroid courses
- Age-related decline in libido and sexual function
Research and Studies:
Clinical studies confirm:
- 400-600% increase in LH levels after Kisspeptin-10 injection
- Restoration of ovulatory cycles in 70% of women with anovulation
- Improvement of spermogram parameters in 65% of men with oligospermia
- Normalization of menstrual cycle in 80% of patients with disorders
- Efficacy in treatment of functional hypothalamic amenorrhea
- Hypogonadotropic hypogonadism in men and women
- Ovulatory function and menstrual cycle disorders
- Functional infertility of unknown origin
- Age-related decline in sexual function and libido
- Rehabilitation after anabolic steroid use
The drug is dissolved in 1-2 ml of sterile water for injections and administered subcutaneously. Standard dosage is 100-200 mcg 1-2 times daily. Treatment course duration is determined individually and usually lasts 1-3 months.
Contraindications:
- Hormone-dependent malignant tumors
- Pregnancy and lactation period
- Severe renal and hepatic insufficiency
- Undiagnosed uterine bleeding
- Individual hypersensitivity
Side Effects:
- Redness and itching at injection site
- Transient headache
- Nausea and abdominal discomfort
- Emotional lability
- Breast tenderness
