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ARSENAM (Arsenic Trioxide)
# Anticancer Agents

ARSENAM (Arsenic Trioxide)

Active ingredient: Arsenic Trioxide (As₂O₃)
Dosage form: Solution for intravenous infusion
Concentration: 1 mg/mL
Volume: 10 mL per vial
Packaging: Sterile vial in individual box

 

Disease Group:

Oncohematology

Acute Promyelocytic Leukemia (APL)

Цена: 342 ₽
Manufacturer: GLS Pharma Ltd., India Store between 15°C and 30°C in the original packaging, protected from light Prescription only; hospital use under strict medical supervision Manufactured in compliance with WHO-GMP standards
Description
Indications for use
Directions for use
Contraindications and side effects
Application for wholesale buyers
  • Acute promyelocytic leukemia (APL), relapsed or refractory
  • May be used in combination regimens or as monotherapy
  • Can be administered when all-trans retinoic acid (ATRA)-based therapies are not suitable or tolerated
  • Administered as a slow intravenous infusion
  • Recommended dose: 0.15 mg/kg body weight per day
  • Duration depends on treatment protocol: induction of remission followed by consolidation or maintenance
  • Infusion duration: 1 to 2 hours under medical supervision
  • Not for bolus injection

To be prescribed and administered only by a hematologist-oncologist in a hospital setting.

Contraindications:

  • Known hypersensitivity to arsenic or any component of the formulation
  • Severe cardiac arrhythmias, including QT interval prolongation
  • Pregnancy and breastfeeding (unless life-threatening condition warrants)

Possible Side Effects:

  • Leukocytosis, hyperglycemia
  • Differentiation syndrome (in APL patients)
  • QT prolongation and arrhythmias
  • Electrolyte disturbances (hypokalemia, hypomagnesemia)
  • Nausea, headache, skin rashes

In case of severe symptoms, stop infusion immediately and consult a oncologist.

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