LEUCOKAST is an active folate form that acts as a chemoprotective agent in methotrexate therapy.
Recommended for:
Patients receiving high-dose methotrexate treatment
Reducing chemotherapy side effects
Enhancing 5-fluorouracil efficacy in colorectal cancer treatment
Managing folate deficiency or poisoning by folate antagonists
High-dose methotrexate toxicity treatment
Chemotherapy modulator with 5-FU in colorectal cancer
Folate deficiency management
Folinic acid rescue after antimetabolite chemotherapy
LEUCOKAST is administered intravenously or intramuscularly depending on the treatment protocol. Dosage and frequency are tailored by the physician based on methotrexate levels and patient condition.
Contraindications:
Known hypersensitivity to leucovorin
Pernicious anaemia or B12-deficient anaemia
Severe adverse reactions to 5-FU
Side Effects:
Allergic reactions (rash, itching, swelling)
Fatigue
Gastrointestinal issues: nausea, diarrhoea
Leucopenia (in combination regimens)
