MEGALIS-5 contains tadalafil, a selective inhibitor of the phosphodiesterase type 5 enzyme. During sexual stimulation, cyclic guanosine monophosphate (cGMP) is produced in penile tissues. cGMP promotes relaxation of smooth muscle and increased blood flow. Tadalafil inhibits the breakdown of cGMP, thereby supporting the physiological process required to achieve and maintain an erection.
Recommended for:
Tadalafil does not produce an erection on its own; sexual stimulation is required for its effect.
Research and clinical evidence:
The primary indication is the treatment of erectile dysfunction in adult men.
Tadalafil inhibits PDE-5, increasing cGMP levels in response to sexual stimulation. This promotes relaxation of penile smooth muscle and increased local blood flow, supporting the development and maintenance of an erection.
The medication does not increase sexual desire and does not protect against sexually transmitted infections.
Tadalafil 5 mg may be used as a once-daily treatment when this regimen has been prescribed by a healthcare professional. The tablet is taken orally with water and may be taken with or without food. With daily treatment, it should be taken at approximately the same time each day. The dose and treatment duration should be determined by a healthcare professional based on the patient's medical condition, other diseases, and concomitant medications. The dose should not be increased without medical advice.
Side Effects
Sudden loss of vision or hearing, severe chest pain, or an erection lasting more than 4 hours requires immediate medical attention.
