How it works:
Tacrolimus inhibits T-cell activation, thus reducing immune responses responsible for organ rejection or autoimmune inflammation. It is suitable for long-term immune modulation when other therapies are insufficient.
Recommended for:
Patients after liver, kidney, or heart transplant
Severe autoimmune diseases (e.g., lupus, dermatomyositis)
Individuals unresponsive to conventional immunosuppressants
Prevention and treatment of transplant rejection
Management of autoimmune diseases
Administered orally, usually twice daily with or without food. The dosage is individually adjusted and monitored through blood level testing.
Contraindications:
Hypersensitivity to tacrolimus or macrolide antibiotics
Active infectious diseases
Severe hepatic impairment
Side effects:
Tremors, headaches
Elevated blood pressure
Renal dysfunction
Post-transplant diabetes
Increased risk of infections
Risk of lymphoproliferative disorders and malignancies
