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By Sacred Leaves Global Medical News | August 2025
Melatonin and chamomile extract are two well-known natural ingredients that help the body relax and fall asleep more easily. One regulates circadian rhythms, the other works gently through the nervous system. Together, they form a harmonious combination for those seeking a mild and safe remedy to improve sleep and reduce stress.
Melatonin is a hormone naturally produced by the pineal gland in the brain. It regulates circadian rhythms—your body's internal clock that signals when to sleep and when to wake up. Melatonin production may decrease with age, stress, artificial lighting in the evening, or jet lag.
When taken orally (most commonly in tablet form), melatonin can:
help you fall asleep faster,
improve sleep quality (more deep sleep phases),
ease jet lag and travel-related sleep disruption,
reduce insomnia symptoms, especially in older adults.
Chamomile (Matricaria chamomilla) has been used in traditional medicine for centuries. Its key active components—apigenin, chamazulene, and bisabolol—have calming, antispasmodic, and anti-inflammatory effects.
Effects of chamomile extract include:
calming the nervous system and reducing anxiety,
helping with stress-related insomnia,
relaxing the muscles of the stomach and intestines (especially during nervous tension),
acting gently without causing dependence.
While melatonin manages the biological clock, chamomile eases anxiety and physically relaxes the body. This combination is especially useful for:
people with anxious thoughts at bedtime,
those who struggle to fall asleep due to stress,
older adults who are sensitive to pharmaceutical sleep aids,
shift workers or frequent travelers.
Melatonin levels naturally rise between 9:00 PM and 3:00 AM. That’s why supplements are best taken 30–60 minutes before bedtime.
Chamomile tea contains less active ingredient than concentrated extracts but still offers a mild relaxing effect.
Melatonin may support adaptation for night-shift workers or those switching time zones.
Melatonin and chamomile are natural allies that can help restore sleep and reduce stress without harsh side effects. Their combination is ideal for sensitive individuals or those seeking a gentle, effective way to align their rhythm with life’s demands. As always, consult a healthcare provider before starting regular use—especially if you're taking other medications.
Research:
A randomized meta-analysis showed that melatonin reduces sleep onset time by an average of 7–12 minutes and improves overall sleep structure.
[PubMed - https://pubmed.ncbi.nlm.nih.gov/24798265/]
In a double-blind study involving elderly participants, chamomile extract showed moderate improvements in sleep quality.
[PubMed - https://pubmed.ncbi.nlm.nih.gov/24831094/]
Apigenin in chamomile binds to GABA receptors, mimicking the effect of sedatives but without side effects.
[SpringerLink - https://link.springer.com/article/10.1007/s00210-005-0048-5]